Biotechnology - Organic Chemistry - Nanoscience
Covalent Chemistry Control of Nucleic Acid Nanotechnology
Mesoscale Molecular Engineering
Welcome to the Lukeman Lab
News
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May 2025 Lukeman: Promotion to Full Professor confirmed. Seems like time for an appropriate comic
January 2025 The lily-pad biosensor paper is FINALLY out in PNAS
December 2023 Welcome to our new trainees: Elijah, Aohona and Julia!
December 2023 Almost a long a gestation as the 2020 paper, * finally *, a preprint
with co-authors from Caltech, Johns Hopkins, U Sherbrooke, UCSB, UCLA and MIT describing a first: a modular, easily adaptable, ultra-sensitive, highest-gain, regeneratable electrochemical biosensor using a “lily-pad” origami mechanism.
Thanks to Army Research Office and St. John's for long-term support of this project. Hopefully coming to a snazzy journal venue near you soon.....
June 2023 Stay tuned for a preprint on some orgiami electrochemical biosensing work! Any day now!
May 2023 LukemanLab wins a $280k, 3 year, new ARO grant to study some fancy DNA electrochemical crosslinking technology! More on this soon.
May 2022 Back to the lab!
Jan 2022 Welcome to our new trainees, Nafisah, Yae Eun and Alex
November 2021 RIP Ned Seeman
The Maass Lab put it best:
Ned Seeman passed away. His language was salty.
He hated dress suits and loved root beer.
He cared about people and even more about structural control of DNA.
He combined creativity, aestheticism,
ruthless control of his experiments
and zero bullshit tolerance.
Farewell, Ned.
April 2021 After a COVID-induced hiatus, back to the lab!
Jun 2020 The summation of 8 years of hard work! A paper published in Nanoscale
In collaboration with UCSB, Johns Hopkins and Ohio State Chemists and Mechanical Engineers, we demonstrate the first DNA Origami electrochemical biosensor capable of recognizing virus-sized objects (and not their subunits!).
We hope others run with this technology and make origami sing in real-world, clinically relevant detection of mesoscale analytes!
Congrats to all involved but particularly Lukemanlab members: Alex, Muaz, Kate F, Natalie and Tammy for your kickass work!
And thanks to ARO & St. John's for their support of a long gestating project!
March 2020 Welp! We go virtual.
Jan 2020 Welcome to our new lab trainees Maria and Jeremy!
November 2019 Congrats to Kate, Natalie, Tammy, Phuong and Angela for their Bronze award at Biomod 2019! Project site
June 2019 A paper with Lukeman as co-author is published in ACS Nano: ‘Designing Higher Resolution Self-Assembled 3D DNA Crystals via Strand Terminus Modifications’
May 2019 Welcome to our new lab members, Phuong and Angela!
April 2019 Lukeman presents a poster at FNANO19
April 2019 Alex, Muaz, Kate, Natalie and Tammy present a poster at St Johns Student research Month
March 2019 LukemanLab wins a $225k, 3 year, new ARO grant to study the electrochemical behavior of DNA origami biosensors
May 2018 Welcome to our new lab members, Natalie, Yekaterina and Tammy!
Nov 2017 Congrats to Alison, Alex, Muaz, Carlotta & Chris for their Bronze award at Biomod 2017 Project site
Sep 2017 Lukeman wins support for ARO and St John's for a Spring 2018 research leave to learn about electrochemical biosensors at UCSB in the lab of Kevin Plaxco
May 2017 Welcome to our new Lab Members: Alison & Muaz!
April 2017 Chris, Alex and Carlotta Present a poster at St. John's student research month
May 2016. Welcome to our new Lab Members, Alex and Carlotta!
Positions available
The LukemanLab is open to applicants from eager St. John's
undergraduate and master's students.
We also accept dedicated high school students from the local area.
Contact Lukeman to be put on a waiting list.